Regulation of Genome Maintenance by Chromatin-Associated Protein Degradation. Dynamics of Proteostasis Networks in Stress Response and Aging. Proteostasis in Development and Aging. For more information about the Hoppe Lab please visit www.

Regulation of cyto-architecture in non-melanoma skin cancer. Polarity proteins in melanocyte homeostasis and melanoma. Research Group Cell Polarity and Cancer. Cell polarization is crucial for development and tissue homeostasis, and aberrant polarity contributes to various diseases. The research group of Sandra Iden investigates functions of polarity proteins in. Epithelial regeneration and stress responses.

Our lab investigates how the cytoskeleton is regulated by post-translational lysine-acetylation.

Institute for Genome Stability in Ageing and Disease. Das Geheimnis des menschlichen Alterns. Die überraschenden Erkenntnisse der noch jungen Alternsforschung. To unravel the molecular mechanism through which DNA damage contributes to ageing we are using the genetic model organism Caenorhabditis elegans as well as mammalian disease models. Hui-Ling Ou defends her PhD. On 28 June 2016 Hui-Ling Ou successfully defended her PhD Thesis. We congratulate Arturo Bujarrabal again, as he re.

Splicing in development and disease. In combination with molecular and cell biology techniques, biochemistry and genomic approaches. PhD and Postdoc positions available.